Histological OF cholangitis
The
pathological lesions at the stage of early cholangitis is limited to
the elements of hepatobiliary lasphère namely [35], [41]:
- Lesion of the common bile duct (C.B.D)
- Liver damage.
LESIONS OF THE C.B.D
Infection of the bile causes inflammation and infection of the bile duct walls that thicken and become the seat of microabscesses.
In the case where the infection is more or less latent, prolonged and repeated, there is scarring resulting in a significant wall thickening that can be considered as a secondary sclerosing cholangitis.
LIVER DAMAGE
The retrograde extension of the infection causes lesions successive
The lesions portales
The Portita, inflammatory appearance of later times, is the first stage with an enlargement of the portal space, which is edematous, congested and infiltrated by neutrophils.
The intrahepatic bile ducts are dilated, severe infection will eventually lead to the formation of microabscesses and a real destruction of biliary structures.
Lobular lesions
The tubules also exhibit epithelial lesions associated with polymorphonuclear infiltration with evidence of cholestasis.
The impact of parenchymal retention in general and early start centrilobular, resulting in different liver cell changes.
Parenchymal infiltration by neutrophils increases with the degree of retention and infection.
Subsequently formed microabscesses in contact with infected biliary structures, their confluence results in the formation of abscesses areal parenchymal structure that disrupt liver.
More rarely, biliary latent infection is prolonged and leads to repeated bouts of cholangitis and regenerative nodules may be delayed, leading to cirrhosis nonspecific quite exceptional.
THE vesicular lesions and the hepatic pedicle
The vesicular lesions are usually those of chronic calculous cholecystitis.Inflammation more unusually infectious contiguity affecting cellular structures, vascular and lymph, causing a potentially responsible pédiculite pylephlebitis.
- Lesion of the common bile duct (C.B.D)
- Liver damage.
LESIONS OF THE C.B.D
Infection of the bile causes inflammation and infection of the bile duct walls that thicken and become the seat of microabscesses.
In the case where the infection is more or less latent, prolonged and repeated, there is scarring resulting in a significant wall thickening that can be considered as a secondary sclerosing cholangitis.
LIVER DAMAGE
The retrograde extension of the infection causes lesions successive
The lesions portales
The Portita, inflammatory appearance of later times, is the first stage with an enlargement of the portal space, which is edematous, congested and infiltrated by neutrophils.
The intrahepatic bile ducts are dilated, severe infection will eventually lead to the formation of microabscesses and a real destruction of biliary structures.
Lobular lesions
The tubules also exhibit epithelial lesions associated with polymorphonuclear infiltration with evidence of cholestasis.
The impact of parenchymal retention in general and early start centrilobular, resulting in different liver cell changes.
Parenchymal infiltration by neutrophils increases with the degree of retention and infection.
Subsequently formed microabscesses in contact with infected biliary structures, their confluence results in the formation of abscesses areal parenchymal structure that disrupt liver.
More rarely, biliary latent infection is prolonged and leads to repeated bouts of cholangitis and regenerative nodules may be delayed, leading to cirrhosis nonspecific quite exceptional.
THE vesicular lesions and the hepatic pedicle
The vesicular lesions are usually those of chronic calculous cholecystitis.Inflammation more unusually infectious contiguity affecting cellular structures, vascular and lymph, causing a potentially responsible pédiculite pylephlebitis.
08:36
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